Journal of Forensic Science and Medicine

BRIEF COMMUNICATION
Year
: 2020  |  Volume : 6  |  Issue : 3  |  Page : 105--109

U-47700 – Incidence of a novel psychoactive substance in a series of medical examiner cases in Oakland County, MI


Lauren Aiello, Emily Skwarek, Daniel Isenschmidt, Ljubisa J Dragovic 
 Oakland County Medical Examiner's Office, Pontiac, MI, USA

Correspondence Address:
Ljubisa J Dragovic
Oakland County Medical Examiner's Office, 1200 N. Telegraph Road, Pontiac, MI
USA

U-47700 is one of many drugs that have been part of a group of compounds called novel psychoactive substances (NPS). U-47700 is a synthetic opioid agonist developed by Upjohn pharmaceuticals but never approved. The Oakland County Medical Examiner's Office in Pontiac, Michigan, began observing this compound in the fall of 2016, primarily in cases with other drugs of abuse and NPS. This communication described 18 drug-related deaths in which U-47700 was detected. Blood U-47700 concentrations ranged from 0.37 to 370 ng/mL (mean 35 and median 4.9 ng/mL). Other opioids were detected in 83% of the cases. Other drugs present in these cases are described as well as the scene investigation. While only one death was likely due directly to U-47700, the cases described here demonstrate how NPS have become an important consideration in evaluating drug-related deaths today.


How to cite this article:
Aiello L, Skwarek E, Isenschmidt D, Dragovic LJ. U-47700 – Incidence of a novel psychoactive substance in a series of medical examiner cases in Oakland County, MI.J Forensic Sci Med 2020;6:105-109


How to cite this URL:
Aiello L, Skwarek E, Isenschmidt D, Dragovic LJ. U-47700 – Incidence of a novel psychoactive substance in a series of medical examiner cases in Oakland County, MI. J Forensic Sci Med [serial online] 2020 [cited 2021 Jan 21 ];6:105-109
Available from: https://www.jfsmonline.com/article.asp?issn=2349-5014;year=2020;volume=6;issue=3;spage=105;epage=109;aulast=Aiello;type=0