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Year : 2020  |  Volume : 6  |  Issue : 1  |  Page : 1-4

A potential marker DYF371 for differentiating han population from non-han population in Chinese

Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, China

Correspondence Address:
Dejian Lu
Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-Sen University, 74# Zhongshan Road Ii, Guangzhou, 510089
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1735-3327.280892

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DYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities. In total, 37 SNP-short tandem repeat haplotypes were detected. Nine of these 37 haplotypes were unique (24.32%). The gene diversity and discrimination capacity values are 0.8321 and 0.2606, respectively. Furthermore, only five males (5.55%) in the Han samples were determined that they had one copy of allele with SNP T-type and three copies of alleles with SNP C-types, whereas 14 individuals (26.92%) were observed in minorities' samples. The genotype proportion comprising three distinguishing copies of the allele with SNP C-types in Han sample was greatly lower than that in the sample of minorities. Similar results were shown for allele 11C and 10C. Therefore, the alleles of DYF371 with SNP C-type have the potential to differentiate the Han and non-Han Chinese populations.

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