| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 6
| Issue : 1 | Page : 1-4 |
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A potential marker DYF371 for differentiating han population from non-han population in Chinese
Hailun Nan, Dejian Lu
Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, China
Correspondence Address:
Dejian Lu
Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-Sen University, 74# Zhongshan Road Ii, Guangzhou, 510089
China
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1735-3327.280892
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DYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities. In total, 37 SNP-short tandem repeat haplotypes were detected. Nine of these 37 haplotypes were unique (24.32%). The gene diversity and discrimination capacity values are 0.8321 and 0.2606, respectively. Furthermore, only five males (5.55%) in the Han samples were determined that they had one copy of allele with SNP T-type and three copies of alleles with SNP C-types, whereas 14 individuals (26.92%) were observed in minorities' samples. The genotype proportion comprising three distinguishing copies of the allele with SNP C-types in Han sample was greatly lower than that in the sample of minorities. Similar results were shown for allele 11C and 10C. Therefore, the alleles of DYF371 with SNP C-type have the potential to differentiate the Han and non-Han Chinese populations.
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